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Angiotensin II Stimulation of DPP4 Activity Regulates Megalin in the Proximal Tubules

Proteinuria is a marker of incipient kidney injury in many disorders, including obesity. Previously, we demonstrated that megalin, a receptor endocytotic protein in the proximal tubule, is downregulated in obese mice, which was prevented by inhibition of dipeptidyl protease 4 (DPP4). Obesity is thou...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Aroor, Annayya, Zuberek, Marcin, Duta, Cornel, Meuth, Alex, Sowers, James R., Whaley-Connell, Adam, Nistala, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881597/
https://ncbi.nlm.nih.gov/pubmed/27213360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050780
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