DPP4 inhibition mitigates ANG II-mediated kidney immune activation and injury in male mice

Recent evidence suggests that dipeptidyl peptidase-4 (DPP4) inhibition with saxagliptin (Saxa) is renoprotective under comorbid conditions associated with activation of the renin-angiotensin-aldosterone system (RAAS), such as diabetes, obesity, and hypertension, which confer a high cardiovascular ri...

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Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: Nistala, Ravi, Meuth, Alex I., Smith, Cassandra, An, Jianzhong, Habibi, Javad, Hayden, M. R., Johnson, Megan, Aroor, Annayya, Whaley-Connell, Adam, Sowers, James R., McKarns, Susan C., Bender, Shawn B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988815/
https://ncbi.nlm.nih.gov/pubmed/33522410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00565.2020
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