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Angiotensin II Stimulation of DPP4 Activity Regulates Megalin in the Proximal Tubules
Proteinuria is a marker of incipient kidney injury in many disorders, including obesity. Previously, we demonstrated that megalin, a receptor endocytotic protein in the proximal tubule, is downregulated in obese mice, which was prevented by inhibition of dipeptidyl protease 4 (DPP4). Obesity is thou...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4881597/ https://ncbi.nlm.nih.gov/pubmed/27213360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050780 |
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