Angiotensin type 1 receptor resistance to blockade in the opossum proximal tubule cell due to variations in the binding pocket

Blockade of the angiotensin (ANG) II receptor type 1 (AT(1)R) with angiotensin receptor blockers (ARBs) is widely used in the treatment of hypertension. However, ARBs are variably effective in reducing blood pressure, likely due, in part, to polymorphisms in the ARB binding pocket of the AT(1)R. The...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nistala, Ravi, Andresen, Bradley T., Pulakat, Lakshmi, Meuth, Alex, Sinak, Catherine, Mandavia, Chirag, Thekkumkara, Thomas, Speth, Robert C., Whaley-Connell, Adam, Sowers, James R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2013
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625841/
https://ncbi.nlm.nih.gov/pubmed/23389452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00127.2012
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