Phase 2 clinical trial of rapamycin-resistant donor CD4(+) Th2/Th1 (T-Rapa) cells after low-intensity allogeneic hematopoietic cell transplantation

In experimental models, ex vivo induced T-cell rapamycin resistance occurred independent of T helper 1 (Th1)/T helper 2 (Th2) differentiation and yielded allogeneic CD4(+) T cells of increased in vivo efficacy that facilitated engraftment and permitted graft-versus-tumor effects while minimizing gra...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Fowler, Daniel H., Mossoba, Miriam E., Steinberg, Seth M., Halverson, David C., Stroncek, David, Khuu, Hahn M., Hakim, Frances T., Castiello, Luciano, Sabatino, Marianna, Leitman, Susan F., Mariotti, Jacopo, Gea-Banacloche, Juan C., Sportes, Claude, Hardy, Nancy M., Hickstein, Dennis D., Pavletic, Steven Z., Rowley, Scott, Goy, Andre, Donato, Michele, Korngold, Robert, Pecora, Andrew, Levine, Bruce L., June, Carl H., Gress, Ronald E., Bishop, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2013
Fag:
Clinical Trials and Observations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624934/
https://ncbi.nlm.nih.gov/pubmed/23426943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-08-446872
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker