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Differential Gene Expression Profile of First- and Second-Generation T-Rapa Cell Clinical Products

We completed a phase II clinical trial evaluating rapamycin-resistant allogeneic T cells (T-Rapa) and now are evaluating a T-Rapa product manufactured in 6-days (T-Rapa(6)) rather than 12-days (T-Rapa(12)). Using gene expression microarrays, we addressed our hypothesis that the two products would ex...

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Detalhes bibliográficos
Main Authors: Castiello, Luciano, Mossoba, Miriam, Viterbo, Antonella, Sabatino, Marianna, Fellowes, Vicki, Foley, Jason E., Winterton, Matthew, Halverson, David C., Civini, Sara, Jin, Ping, Fowler, Daniel H., Stroncek, David F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148082/
https://ncbi.nlm.nih.gov/pubmed/23352462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcyt.2012.12.008
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