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Structural Integrity of the B24 Site in Human Insulin Is Important for Hormone Functionality
Despite the recent first structural insight into the insulin-insulin receptor complex, the role of the C terminus of the B-chain of insulin in this assembly remains unresolved. Previous studies have suggested that this part of insulin must rearrange to reveal amino acids crucial for interaction with...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624407/ https://ncbi.nlm.nih.gov/pubmed/23447530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.448050 |
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