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Implications for the active form of human insulin based on the structural convergence of highly active hormone analogues
Insulin is a key protein hormone that regulates blood glucose levels and, thus, has widespread impact on lipid and protein metabolism. Insulin action is manifested through binding of its monomeric form to the Insulin Receptor (IR). At present, however, our knowledge about the structural behavior of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836629/ https://ncbi.nlm.nih.gov/pubmed/20133841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911785107 |
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