Screening Compounds with a Novel High-Throughput ABCB1-Mediated Efflux Assay Identifies Drugs with Known Therapeutic Targets at Risk for Multidrug Resistance Interference

ABCB1, also known as P-glycoprotein (P-gp) or multidrug resistance protein 1 (MDR1), is a membrane-associated multidrug transporter of the ATP-binding cassette (ABC) transporter family. It is one of the most widely studied transporters that enable cancer cells to develop drug resistance. Reliable hi...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ansbro, Megan R., Shukla, Suneet, Ambudkar, Suresh V., Yuspa, Stuart H., Li, Luowei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622673/
https://ncbi.nlm.nih.gov/pubmed/23593196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060334
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