Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice

Genetic and molecular approaches have been critical for elucidating the mechanism of the mammalian circadian clock. Here, we demonstrate that the ClockΔ19 mutant behavioral phenotype is significantly modified by mouse strain genetic background. We map a suppressor of the ClockΔ19 mutation to a ∼900...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Shimomura, Kazuhiro, Kumar, Vivek, Koike, Nobuya, Kim, Tae-Kyung, Chong, Jason, Buhr, Ethan D, Whiteley, Andrew R, Low, Sharon S, Omura, Chiaki, Fenner, Deborah, Owens, Joseph R, Richards, Marc, Yoo, Seung-Hee, Hong, Hee-Kyung, Vitaterna, Martha H, Bass, Joseph, Pletcher, Mathew T, Wiltshire, Tim, Hogenesch, John, Lowrey, Phillip L, Takahashi, Joseph S
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2013
Fag:
Genomics and Evolutionary Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622178/
https://ncbi.nlm.nih.gov/pubmed/23580255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00426
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker