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mTOR Inhibition Elicits a Dramatic Response in PI3K-Dependent Colon Cancers
The phosphatidylinositide-3-kinase (PI3K) signaling pathway is critical for multiple cellular functions including metabolism, proliferation, angiogenesis, and apoptosis, and is the most commonly altered pathway in human cancers. Recently, we developed a novel mouse model of colon cancer in which tum...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3621889/ https://ncbi.nlm.nih.gov/pubmed/23593290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060709 |
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