Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations

Therapeutic targeting of the phosphoinositide 3-kinase (PI3K) pathway is an active area of research in multiple cancer types, including breast and endometrial cancers. This pathway is commonly altered in cancer and plays an integral role in numerous vital cellular functions. Mutations in the PIK3CA...

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Detaylı Bibliyografya
Yayımlandı:Mol Cancer Res
Asıl Yazarlar: Foley, Tyler M., Payne, Susan N., Pasch, Cheri A., Yueh, Alex E., Van De Hey, Dana R., Korkos, Demetra P., Clipson, Linda, Maher, Molly E., Matkowskyj, Kristina A., Newton, Michael A., Deming, Dustin A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550373/
https://ncbi.nlm.nih.gov/pubmed/28184015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0256
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