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Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K
The phosphoinositide 3-kinase (PI3K) signaling pathway is critical for multiple important cellular functions, and is one of the most commonly altered pathways in human cancers. We previously developed a mouse model in which colon cancers were initiated by a dominant active PI3K p110-p85 fusion prote...
Shranjeno v:
| izdano v: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4749659/ https://ncbi.nlm.nih.gov/pubmed/26863299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148730 |
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