Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K

The phosphoinositide 3-kinase (PI3K) signaling pathway is critical for multiple important cellular functions, and is one of the most commonly altered pathways in human cancers. We previously developed a mouse model in which colon cancers were initiated by a dominant active PI3K p110-p85 fusion prote...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yueh, Alexander E., Payne, Susan N., Leystra, Alyssa A., Van De Hey, Dana R., Foley, Tyler M., Pasch, Cheri A., Clipson, Linda, Matkowskyj, Kristina A., Deming, Dustin A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749659/
https://ncbi.nlm.nih.gov/pubmed/26863299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148730
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