Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K

The phosphoinositide 3-kinase (PI3K) signaling pathway is critical for multiple important cellular functions, and is one of the most commonly altered pathways in human cancers. We previously developed a mouse model in which colon cancers were initiated by a dominant active PI3K p110-p85 fusion prote...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Yueh, Alexander E., Payne, Susan N., Leystra, Alyssa A., Van De Hey, Dana R., Foley, Tyler M., Pasch, Cheri A., Clipson, Linda, Matkowskyj, Kristina A., Deming, Dustin A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749659/
https://ncbi.nlm.nih.gov/pubmed/26863299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148730
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi