PIK3CA and APC Mutations are Synergistic in the Development of Intestinal Cancers

Human colorectal cancers are known to possess multiple mutations, though how these mutations interact in tumor development and progression has not been fully investigated. We have previously described the FCPIK3ca* murine colon cancer model which expresses a constitutively activated phosphoinositide...

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Bibliografiske detaljer
Main Authors: Deming, Dustin A., Leystra, Alyssa A., Nettekoven, Laura, Sievers, Chelsea, Miller, Devon, Middlebrooks, Malisa, Clipson, Linda, Albrecht, Dawn, Bacher, Jeff, Washington, Mary Kay, Weichert, Jamey, Halberg, Richard B.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883937/
https://ncbi.nlm.nih.gov/pubmed/23708654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.167
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