Mice Expressing Activated PI3K Rapidly Develop Advanced Colon Cancer

Aberrations in the phosphatidylinositide-3-kinase (PI3K) signaling pathway play a key role in the pathogenesis of numerous cancers by altering cellular growth, metabolism, proliferation, and apoptosis (1). Mutations in the catalytic domain of PI3K that generate a dominantly active kinase are commonl...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Leystra, Alyssa A., Deming, Dustin A., Zahm, Christopher D., Farhoud, Mohammed, Paul Olson, Terrah J., Hadac, Jamie N., Nettekoven, Laura A., Albrecht, Dawn M., Clipson, Linda, Sullivan, Ruth, Washington, Mary Kay, Torrealba, Jose R., Weichert, Jamey P., Halberg, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645915/
https://ncbi.nlm.nih.gov/pubmed/22525701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-4097
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares