Transformation of epithelial cells through recruitment leads to polyclonal intestinal tumors

Intestinal tumors from mice and humans can have a polyclonal origin. Statistical analyses indicate that the best explanation for this source of intratumoral heterogeneity is the presence of interactions among multiple progenitors. We sought to better understand the nature of these interactions. An i...

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Autori principali: Thliveris, Andrew T., Schwefel, Brittany, Clipson, Linda, Plesh, Lauren, Zahm, Christopher D., Leystra, Alyssa A., Washington, Mary Kay, Sullivan, Ruth, Deming, Dustin A., Newton, Michael A., Halberg, Richard B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710880/
https://ncbi.nlm.nih.gov/pubmed/23798428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303064110
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