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Molecular chaperones protect against JNK- and Nmnat-regulated axon degeneration in Drosophila

Axon degeneration is observed at the early stages of many neurodegenerative conditions and this often leads to subsequent neuronal loss. We previously showed that inactivating the c-Jun N-terminal kinase (JNK) pathway leads to axon degeneration in Drosophila mushroom body (MB) neurons. To understand...

詳細記述

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書誌詳細
主要な著者: Rallis, Andrew, Lu, Bingwei, Ng, Julian
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619812/
https://ncbi.nlm.nih.gov/pubmed/23264732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.117259
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