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Why is NMNAT Protective against Neuronal Cell Death and Axon Degeneration, but Inhibitory of Axon Regeneration?

Nicotinamide mononucleotide adenylyltransferase (NMNAT), a key enzyme for NAD(+) synthesis, is well known for its activity in neuronal survival and attenuation of Wallerian degeneration. Recent investigations in invertebrate models have, however, revealed that NMNAT activity negatively impacts upon...

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Detalhes bibliográficos
Publicado no:Cells
Autor principal: Tang, Bor Luen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468476/
https://ncbi.nlm.nih.gov/pubmed/30901919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8030267
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