Why is NMNAT Protective against Neuronal Cell Death and Axon Degeneration, but Inhibitory of Axon Regeneration?

Nicotinamide mononucleotide adenylyltransferase (NMNAT), a key enzyme for NAD<sup>+</sup> synthesis, is well known for its activity in neuronal survival and attenuation of Wallerian degeneration. Recent investigations in invertebrate models have, however, revealed that NMNAT activity neg...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Autor principal: Bor Luen Tang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-03-01
Colecção:Cells
Assuntos:
axon regeneration
neuroprotection
nicotinamide mononucleotide adenylyltransferase (NMNAT)
nicotinamide adenine dinucleotide (NAD<sup>+</sup>)
phosphatase and tensin homolog (PTEN)
SIRT1
Acesso em linha:https://www.mdpi.com/2073-4409/8/3/267
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados