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Signal strength and signal duration define two distinct aspects of JNK-regulated axon stability

Signaling proteins often control multiple aspects of cell morphogenesis. Yet the mechanisms that govern their pleiotropic behavior are often unclear. Here we show activity levels and timing mechanisms determine distinct aspects of Jun N-terminal kinase (JNK) pathway dependent axonal morphogenesis in...

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Detalhes bibliográficos
Main Authors: Rallis, Andrew, Moore, Coralie, Ng, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845820/
https://ncbi.nlm.nih.gov/pubmed/20035736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.12.016
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