Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure

The serotonin receptor 2C plays a central role in mood and appetite control. It undergoes pre-mRNA editing as well as alternative splicing. The RNA editing suggests that the pre-mRNA forms a stable secondary structure in vivo. To identify substances that promote alternative exons inclusion, we set u...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shen, Manli, Bellaousov, Stanislav, Hiller, Michael, de La Grange, Pierre, Creamer, Trevor P., Malina, Orit, Sperling, Ruth, Mathews, David H., Stoilov, Peter, Stamm, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616728/
https://ncbi.nlm.nih.gov/pubmed/23393189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt063
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados