Differential Type I Interferon-dependent Transgene Silencing of Helper-dependent Adenoviral vs. Adeno-associated Viral Vectors In Vivo

We previously dissected the components of the innate immune response to Helper-dependent adenoviral vectors (HDAds) using genetic models, and demonstrated that multiple pattern recognition receptor signaling pathways contribute to this host response to HDAds in vivo. Based on analysis of cytokine ex...

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Hlavní autoři: Suzuki, Masataka, Bertin, Terry K, Rogers, Geoffrey L, Cela, Racel G, Zolotukhin, Irene, Palmer, Donna J, Ng, Philip, Herzog, Roland W, Lee, Brendan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616533/
https://ncbi.nlm.nih.gov/pubmed/23319058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.277
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