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Neonatal helper-dependent adenoviral vector gene therapy mediates correction of hemophilia A and tolerance to human factor VIII

Neonatal gene therapy is a promising strategy for treating a number of congenital diseases diagnosed shortly after birth as expression of therapeutic proteins during postnatal life may limit the pathologic consequences and result in a potential “cure.” Hemophilia A is often complicated by the develo...

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Autors principals: Hu, Chuhong, Cela, Racel G., Suzuki, Masataka, Lee, Brendan, Lipshutz, Gerald S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033287/
https://ncbi.nlm.nih.gov/pubmed/21245323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015571108
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