Treatment of osteoarthritis using a helper-dependent adenoviral vector retargeted to chondrocytes

Osteoarthritis (OA) is a joint disease characterized by degeneration of the articular cartilage, subchondral bone remodeling, and secondary inflammation. It is among the top three causes of chronic disability, and currently there are no treatment options to prevent disease progression. The localized...

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Bibliographic Details
Published in:Mol Ther Methods Clin Dev
Main Authors: Ruan, Merry ZC, Cerullo, Vincenzo, Cela, Racel, Clarke, Chris, Lundgren-Akerlund, Evy, Barry, Michael A, Lee, Brendan HL
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008224/
https://ncbi.nlm.nih.gov/pubmed/27626040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.8
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