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Treatment of osteoarthritis using a helper-dependent adenoviral vector retargeted to chondrocytes

Osteoarthritis (OA) is a joint disease characterized by degeneration of the articular cartilage, subchondral bone remodeling, and secondary inflammation. It is among the top three causes of chronic disability, and currently there are no treatment options to prevent disease progression. The localized...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Ruan, Merry ZC, Cerullo, Vincenzo, Cela, Racel, Clarke, Chris, Lundgren-Akerlund, Evy, Barry, Michael A, Lee, Brendan HL
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008224/
https://ncbi.nlm.nih.gov/pubmed/27626040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.8
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