Differential Type I Interferon-dependent Transgene Silencing of Helper-dependent Adenoviral vs. Adeno-associated Viral Vectors In Vivo

We previously dissected the components of the innate immune response to Helper-dependent adenoviral vectors (HDAds) using genetic models, and demonstrated that multiple pattern recognition receptor signaling pathways contribute to this host response to HDAds in vivo. Based on analysis of cytokine ex...

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Bibliografske podrobnosti
Main Authors: Suzuki, Masataka, Bertin, Terry K, Rogers, Geoffrey L, Cela, Racel G, Zolotukhin, Irene, Palmer, Donna J, Ng, Philip, Herzog, Roland W, Lee, Brendan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616533/
https://ncbi.nlm.nih.gov/pubmed/23319058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.277
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