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Structural Landscape of the Proline-Rich Domain of Sos1 Nucleotide Exchange Factor
Despite its key role in mediating a plethora of cellular signaling cascades pertinent to health and disease, little is known about the structural landscape of the proline-rich (PR) domain of Sos1 guanine nucleotide exchange factor. Herein, using a battery of biophysical tools, we provide evidence th...
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Autors principals: | , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2013
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3615079/ https://ncbi.nlm.nih.gov/pubmed/23528987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2013.02.008 |
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