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Assembly of the Sos1-Grb2-Gab1 Ternary Signaling Complex Is Under Allosteric Control

Allostery has evolved as a form of local communication between interacting protein partners allowing them to quickly sense changes in their immediate vicinity in response to external cues. Herein, using isothermal titration calorimetry (ITC) in conjunction with circular dichroism (CD) and macromolec...

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Detalhes bibliográficos
Main Authors: McDonald, Caleb B., Seldeen, Kenneth L., Deegan, Brian J., Bhat, Vikas, Farooq, Amjad
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819574/
https://ncbi.nlm.nih.gov/pubmed/20005866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.12.011
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