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Assembly of the Sos1-Grb2-Gab1 Ternary Signaling Complex Is Under Allosteric Control

Allostery has evolved as a form of local communication between interacting protein partners allowing them to quickly sense changes in their immediate vicinity in response to external cues. Herein, using isothermal titration calorimetry (ITC) in conjunction with circular dichroism (CD) and macromolec...

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Autori principali: McDonald, Caleb B., Seldeen, Kenneth L., Deegan, Brian J., Bhat, Vikas, Farooq, Amjad
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819574/
https://ncbi.nlm.nih.gov/pubmed/20005866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.12.011
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