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Comparison of the Intracellular Trafficking Itinerary of CTLA-4 Orthologues

CTLA-4 is an essential inhibitor of T cell immune responses. At steady state, most CTLA-4 resides in intracellular compartments due to constitutive internalisation mediated via a tyrosine based endocytic motif (YVKM) within the cytoplasmic domain. This domain is highly conserved in mammals suggestin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kaur, Satdip, Qureshi, Omar S., Sansom, David M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614947/
https://ncbi.nlm.nih.gov/pubmed/23565286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060903
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