Characterization of CTLA4 Trafficking and Implications for Its Function

CTLA4 is an essential negative regulator of T-cell immune responses and a key checkpoint regulating autoimmunity and antitumor responses. Genetic mutations resulting in quantitative defects in the CTLA4 pathway are also associated with the development of immune dysregulation syndromes in humans. It...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys J
Prif Awduron: Khailaie, Sahamoddin, Rowshanravan, Behzad, Robert, Philippe A., Waters, Erin, Halliday, Neil, Badillo Herrera, Jesus David, Walker, Lucy S.K., Sansom, David M., Meyer-Hermann, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2018
Pynciau:
Cell Biophysics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170599/
https://ncbi.nlm.nih.gov/pubmed/30219287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.08.020
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