Characterization of CTLA4 Trafficking and Implications for Its Function

CTLA4 is an essential negative regulator of T-cell immune responses and a key checkpoint regulating autoimmunity and antitumor responses. Genetic mutations resulting in quantitative defects in the CTLA4 pathway are also associated with the development of immune dysregulation syndromes in humans. It...

詳細記述

保存先:
書誌詳細
出版年:Biophys J
主要な著者: Khailaie, Sahamoddin, Rowshanravan, Behzad, Robert, Philippe A., Waters, Erin, Halliday, Neil, Badillo Herrera, Jesus David, Walker, Lucy S.K., Sansom, David M., Meyer-Hermann, Michael
フォーマット: Artigo
言語:Inglês
出版事項: The Biophysical Society 2018
主題:
Cell Biophysics
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170599/
https://ncbi.nlm.nih.gov/pubmed/30219287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.08.020
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