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Characterization of CTLA4 Trafficking and Implications for Its Function
CTLA4 is an essential negative regulator of T-cell immune responses and a key checkpoint regulating autoimmunity and antitumor responses. Genetic mutations resulting in quantitative defects in the CTLA4 pathway are also associated with the development of immune dysregulation syndromes in humans. It...
Guardat en:
| Publicat a: | Biophys J |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Biophysical Society
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6170599/ https://ncbi.nlm.nih.gov/pubmed/30219287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.08.020 |
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