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CTLA-4: a moving target in immunotherapy
CD28 and CTLA-4 are members of a family of Immunoglobulin-related receptors that are responsible for various aspects of T cell immune regulation. The family includes CD28, CTLA-4 and ICOS as well as other proteins including PD-1, BTLA and TIGIT. These receptors have both stimulatory (CD28, ICOS) as...
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| Publicado en: | Blood |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6317697/ https://ncbi.nlm.nih.gov/pubmed/29118008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-06-741033 |
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