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CTLA-4: a moving target in immunotherapy

CD28 and CTLA-4 are members of a family of Immunoglobulin-related receptors that are responsible for various aspects of T cell immune regulation. The family includes CD28, CTLA-4 and ICOS as well as other proteins including PD-1, BTLA and TIGIT. These receptors have both stimulatory (CD28, ICOS) as...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood
Prif Awduron: Rowshanravan, Behzad, Halliday, Neil, Sansom, David M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317697/
https://ncbi.nlm.nih.gov/pubmed/29118008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-06-741033
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