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High throughput screen identifies cyclic nucleotide analogs that inhibit Prostatic acid phosphatase
The secretory and transmembrane isoforms of Prostatic acid phosphatase (PAP) can dephosphorylate extracellular adenosine 5′-monophosphate (AMP) to adenosine, classifying PAP as an ectonucleotidase. Currently, there are no compounds that inhibit PAP in living cells. To identify small molecule modulat...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3608840/ https://ncbi.nlm.nih.gov/pubmed/23190738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057112468613 |
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