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A high-throughput approach for identification of novel general anesthetics.
Anesthetic development has been a largely empirical process. Recently, we described a GABAergic mimetic model system for anesthetic binding, based on apoferritin and an environment-sensitive fluorescent probe. Here, a competition assay based on 1-aminoanthracene and apoferritin has been taken to a h...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2009-09-01
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| Series: | PLoS ONE |
| Acceso en liña: | http://europepmc.org/articles/PMC2746312?pdf=render |
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