Discovery of a Novel General Anesthetic Chemotype Using High-throughput Screening

BACKGROUND: The development of novel anesthetics has historically been a process of combined serendipity and empiricism, with most recent new anesthetics developed via modification of existing anesthetic structures. METHODS: Using a novel high-throughput screen employing the fluorescent anesthetic 1...

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Publicado no:Anesthesiology
Main Authors: McKinstry-Wu, Andrew R., Bu, Weiming, Rai, Ganesha, Lea, Wendy A., Weiser, Brian P., Liang, David F., Simeonov, Anton, Jadhav, Ajit, Maloney, David J., Eckenhoff, Roderic G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300529/
https://ncbi.nlm.nih.gov/pubmed/25603205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000505
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