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A High Throughput Assay to Identify Small Molecule Modulators of Prostatic Acid Phosphatase

Prostatic acid phosphatase (PAP) is expressed in nociceptive neurons and functions as an ectonucleotidase. Injection of the secretory isoform of PAP has potent antinociceptive effects in mouse models of chronic pain. These data suggested that a small molecule activator of PAP may have utility as a n...

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Detalhes bibliográficos
Main Authors: Larsen, Rylan S, Zylka, Mark J, Scott, John E
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Open 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808025/
https://ncbi.nlm.nih.gov/pubmed/20161835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1875397300903010042
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