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A High Throughput Assay to Identify Small Molecule Modulators of Alternative pre-mRNA Splicing

Alternative splicing (AS) is an efficient mechanism that involves the generation of transcriptome and protein diversity from a single gene. Defects in pre-mRNA splicing are an important cause of numerous diseases, including cancer. AS of pre-mRNA as a target for cancer therapy has not been well stud...

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Hlavní autoři: Arslan, Ahmet Dirim, He, Xiaolong, Wang, Minxiu, Rumschlag-Booms, Emily, Rong, Lijun, Beck, William T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541474/
https://ncbi.nlm.nih.gov/pubmed/22972848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057112459901
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