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A High Throughput Assay to Identify Small Molecule Modulators of Alternative pre-mRNA Splicing
Alternative splicing (AS) is an efficient mechanism that involves the generation of transcriptome and protein diversity from a single gene. Defects in pre-mRNA splicing are an important cause of numerous diseases, including cancer. AS of pre-mRNA as a target for cancer therapy has not been well stud...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3541474/ https://ncbi.nlm.nih.gov/pubmed/22972848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057112459901 |
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