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Small molecule control of pre-mRNA splicing
SR proteins regulate alternative splicing by binding to exonic sequences where, via an arginine/serine-rich splicing activation domain, they enhance the binding of the spliceosome to the adjacent splice sites. Here, a system is described in which a nontoxic derivative of the small molecule rapamycin...
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright 2005 by RNA Society
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370724/ https://ncbi.nlm.nih.gov/pubmed/15661847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7229705 |
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