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Small molecule control of pre-mRNA splicing
SR proteins regulate alternative splicing by binding to exonic sequences where, via an arginine/serine-rich splicing activation domain, they enhance the binding of the spliceosome to the adjacent splice sites. Here, a system is described in which a nontoxic derivative of the small molecule rapamycin...
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| Hlavní autor: | |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Copyright 2005 by RNA Society
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370724/ https://ncbi.nlm.nih.gov/pubmed/15661847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7229705 |
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