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Small molecule control of pre-mRNA splicing

SR proteins regulate alternative splicing by binding to exonic sequences where, via an arginine/serine-rich splicing activation domain, they enhance the binding of the spliceosome to the adjacent splice sites. Here, a system is described in which a nontoxic derivative of the small molecule rapamycin...

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Hlavní autor: GRAVELEY, BRENTON R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Copyright 2005 by RNA Society 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370724/
https://ncbi.nlm.nih.gov/pubmed/15661847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7229705
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