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A High Throughput Assay to Identify Small Molecule Modulators of Prostatic Acid Phosphatase
Prostatic acid phosphatase (PAP) is expressed in nociceptive neurons and functions as an ectonucleotidase. Injection of the secretory isoform of PAP has potent antinociceptive effects in mouse models of chronic pain. These data suggested that a small molecule activator of PAP may have utility as a n...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Bentham Open
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808025/ https://ncbi.nlm.nih.gov/pubmed/20161835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1875397300903010042 |
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