Epidermal growth factor receptor cytoplasmic domain mutations trigger ligand-independent transformation.
The transforming gene product of avian erythroblastosis virus, v-erbB, is derived from the epidermal growth factor (EGF) receptor but has lost its extracellular ligand-binding domain and was mutated in its cytoplasmic portion, which is thought to be responsible for biological signal generation. We h...
Kaydedildi:
| Yayımlandı: | Mol Cell Biol |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis
1990
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360669/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1971419/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.6.3048-3055.1990 |
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