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Ligand-induced stimulation of epidermal growth factor receptor mutants with altered transmembrane regions.
The epidermal growth factor (EGF) receptor is a transmembrane glycoprotein composed of a large extracellular ligand-binding region connected to the cytoplasmic kinase domain by a single transmembrane (TM) region. To explore the role of the TM region in the process of receptor activation, we have gen...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1988
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282799/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3264402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.24.9567 |
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