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Ligand-induced stimulation of epidermal growth factor receptor mutants with altered transmembrane regions.

The epidermal growth factor (EGF) receptor is a transmembrane glycoprotein composed of a large extracellular ligand-binding region connected to the cytoplasmic kinase domain by a single transmembrane (TM) region. To explore the role of the TM region in the process of receptor activation, we have gen...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kashles, O, Szapary, D, Bellot, F, Ullrich, A, Schlessinger, J, Schmidt, A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282799/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3264402/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.24.9567
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