Ligand-induced stimulation of epidermal growth factor receptor mutants with altered transmembrane regions.

The epidermal growth factor (EGF) receptor is a transmembrane glycoprotein composed of a large extracellular ligand-binding region connected to the cytoplasmic kinase domain by a single transmembrane (TM) region. To explore the role of the TM region in the process of receptor activation, we have gen...

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Bibliographic Details
Main Authors: Kashles, O, Szapary, D, Bellot, F, Ullrich, A, Schlessinger, J, Schmidt, A
Format: Artigo
Language:Inglês
Published: 1988
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC282799/
https://ncbi.nlm.nih.gov/pubmed/3264402
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