Загрузка...
Interaction of human cytochrome P4503A4 with ritonavir analogs
Ritonavir is a HIV protease inhibitor that also potently inactivates cytochrome P450 3A4 (CYP3A4), a major human drug-metabolizing enzyme. To better understand the mechanism of ligand binding and to find strategies for improvement of the inhibitory potency of ritonavir, currently administered to enh...
Сохранить в:
| Главные авторы: | , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606017/ https://ncbi.nlm.nih.gov/pubmed/22410611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2012.02.018 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|