Llwytho...

Interaction of human cytochrome P4503A4 with ritonavir analogs

Ritonavir is a HIV protease inhibitor that also potently inactivates cytochrome P450 3A4 (CYP3A4), a major human drug-metabolizing enzyme. To better understand the mechanism of ligand binding and to find strategies for improvement of the inhibitory potency of ritonavir, currently administered to enh...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sevrioukova, Irina F., Poulos, Thomas L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606017/
https://ncbi.nlm.nih.gov/pubmed/22410611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2012.02.018
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