Loading...
Interaction of human cytochrome P4503A4 with ritonavir analogs
Ritonavir is a HIV protease inhibitor that also potently inactivates cytochrome P450 3A4 (CYP3A4), a major human drug-metabolizing enzyme. To better understand the mechanism of ligand binding and to find strategies for improvement of the inhibitory potency of ritonavir, currently administered to enh...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606017/ https://ncbi.nlm.nih.gov/pubmed/22410611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2012.02.018 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|