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NS309 decreases rat detrusor smooth muscle membrane potential and phasic contractions by activating SK3 channels
BACKGROUND AND PURPOSE: Overactive bladder (OAB) is often associated with abnormally increased detrusor smooth muscle (DSM) contractions. We used NS309, a selective and potent opener of the small or intermediate conductance Ca(2+)-activated K(+) (SK or IK, respectively) channels, to evaluate how SK/...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605870/ https://ncbi.nlm.nih.gov/pubmed/23145946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12049 |
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