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Large conductance Ca(2+)-activated K(+) channel activation with NS1619 decreases myogenic and neurogenic contractions of rat detrusor smooth muscle

Large conductance voltage- and Ca(2+)-activated K(+) channels are important in regulating detrusor smooth muscle (DSM) function. Here, we examined systematically how the BK channel pharmacological activation modulates DSM contractility. NS1619, a potent BK channel activator, was utilized as a pharma...

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Autores principales: Soder, Rupal P., Petkov, Georgi V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193563/
https://ncbi.nlm.nih.gov/pubmed/21914438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2011.08.013
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