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Suppression of human detrusor smooth muscle excitability and contractility via pharmacological activation of large conductance Ca(2+)-activated K(+) channels
Overactive bladder syndrome is frequently associated with increased detrusor smooth muscle (DSM) contractility. We tested the hypothesis that pharmacological activation of the large-conductance voltage- and Ca(2+)-activated K(+) (BK) channel with NS-1619, a selective BK channel opener, reduces the e...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378020/ https://ncbi.nlm.nih.gov/pubmed/22422396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00417.2011 |
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