Role of potassium ion channels in detrusor smooth muscle function and dysfunction

Por Petkov, Georgi V.
Publicado em 2011

Central role of the BK channel in urinary bladder smooth muscle physiology and pathophysiology

Por Petkov, Georgi V.
Publicado em 2014

Identification of Large Conductance Calcium Activated Potassium Channel Accessory β4 Subunit in Rat and Mouse Bladder Smooth Muscle

Por Chen, Muyan, Petkov, Georgi V.
Publicado no J Urol (2009)

Large conductance Ca(2+)-activated K(+) channel activation with NS1619 decreases myogenic and neurogenic contractions of rat detrusor smooth muscle

Por Soder, Rupal P., Petkov, Georgi V.
Publicado em 2011

Activation of muscarinic M(3) receptors inhibits large-conductance voltage- and Ca(2+)-activated K(+) channels in rat urinary bladder smooth muscle cells

Por Parajuli, Shankar P., Petkov, Georgi V.
Publicado em 2013

Functional BK channels facilitate the β(3)-adrenoceptor agonist-mediated relaxation of nerve-evoked contractions in rat urinary bladder smooth muscle isolated strips

Por Afeli, Serge A. Y., Petkov, Georgi V.
Publicado em 2013

Single-channel biophysical and pharmacological characterization of native human large conductance calcium-activated potassium channels in freshly isolated detrusor smooth muscle ce...

Por Malysz, John, Rovner, Eric S., Petkov, Georgi V.
Publicado em 2013

Novel mechanism of hydrogen sulfide-induced guinea pig urinary bladder smooth muscle contraction: role of BK channels and cholinergic neurotransmission

Por Fernandes, Vítor S., Xin, Wenkuan, Petkov, Georgi V.
Publicado no Am J Physiol Cell Physiol (2015)

The Novel K(V)7.2/K(V)7.3 Channel Opener ICA-069673 Reveals Subtype-Specific Functional Roles in Guinea Pig Detrusor Smooth Muscle Excitability and Contractility

Por Provence, Aaron, Malysz, John, Petkov, Georgi V.
Publicado no J Pharmacol Exp Ther (2015)

AB317. SPR-44 Pharmacological activation of individual KCNQ channel subtypes in detrusor smooth muscle represents a promising novel approach for overactive bladder treatment

Por Provence, Aaron, Angoli, Damiano, Petkov, Georgi V.
Publicado no Transl Androl Urol (2016)

Regulation of transient receptor potential melastatin 4 channel by sarcoplasmic reticulum inositol trisphosphate receptors: Role in human detrusor smooth muscle function

Por Provence, Aaron, Rovner, Eric S., Petkov, Georgi V.
Publicado no Channels (Austin) (2017)

K(V)7 Channel Pharmacological Activation by the Novel Activator ML213: Role for Heteromeric K(V)7.4/K(V)7.5 Channels in Guinea Pig Detrusor Smooth Muscle Function

Por Provence, Aaron, Angoli, Damiano, Petkov, Georgi V.
Publicado no J Pharmacol Exp Ther (2018)

Voltage-gated K(+) channels sensitive to stromatoxin-1 regulate myogenic and neurogenic contractions of rat urinary bladder smooth muscle

Por Chen, Muyan, Kellett, Whitney F., Petkov, Georgi V.
Publicado em 2010

Prostaglandin E2 excitatory effects on guinea pig urinary bladder smooth muscle: A novel regulatory mechanism mediated by large-conductance voltage- and Ca(2+)-activated K(+) chann...

Por Parajuli, Shankar P., Provence, Aaron, Petkov, Georgi V.
Publicado em 2014

SK but not IK channels regulate human detrusor smooth muscle spontaneous and nerve-evoked contractions

Por Afeli, Serge A. Y., Rovner, Eric S., Petkov, Georgi V.
Publicado em 2012

BRL37344, a β3-adrenergic receptor agonist, decreases nerve-evoked contractions in human detrusor smooth muscle isolated strips: Role of BK channels

Por Afeli, Serge A. Y., Rovner, Eric S., Petkov, Georgi V.
Publicado em 2013

Molecular Expression and Pharmacological Evidence for a Functional Role of Kv7 Channel Subtypes in Guinea Pig Urinary Bladder Smooth Muscle

Por Afeli, Serge A. Y., Malysz, John, Petkov, Georgi V.
Publicado em 2013

BK Channel-Mediated Relaxation of Urinary Bladder Smooth Muscle: A Novel Paradigm for Phosphodiesterase Type 4 Regulation of Bladder Function

Por Xin, Wenkuan, Li, Ning, Cheng, Qiuping, Petkov, Georgi V.
Publicado em 2014

Constitutively active PKA regulates neuronal acetylcholine release and contractility of guinea pig urinary bladder smooth muscle

Por Xin, Wenkuan, Li, Ning, Fernandes, Vitor S., Petkov, Georgi V.
Publicado no Am J Physiol Renal Physiol (2016)

Do β3-adrenergic receptors play a role in guinea pig detrusor smooth muscle excitability and contractility?

Por Afeli, Serge A. Y., Hristov, Kiril L., Petkov, Georgi V.
Publicado em 2012