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Prostaglandin E2 excitatory effects on guinea pig urinary bladder smooth muscle: A novel regulatory mechanism mediated by large-conductance voltage- and Ca(2+)-activated K(+) channels

Prostaglandin E2 (PGE(2)) is an essential signaling molecule involved in the regulation of detrusor smooth muscle (DSM) function. However, the underlying regulatory mechanism by which PGE(2) augments DSM cell excitability and contractility is not well understood. Here, we investigated whether PGE in...

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Autori principali: Parajuli, Shankar P., Provence, Aaron, Petkov, Georgi V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107080/
https://ncbi.nlm.nih.gov/pubmed/24886877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2014.05.042
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